introduction: tegrity is the most important component for transferring genetic information sperm dna fragmentation is considered a component of male infertility. its assessment comprises conventional semen analysis of which emphasis is placed on its evaluation in fertility clinics. in this study, we investigate the relationship between sperm parameters of motility, morphology, concentration, an...

background: although the effectiveness of ginger as an antioxidant agent has been exploited, little human research has been conducted on its activity on male reproductive functions. objective: this study was designed to investigate the effects of ginger (zingiber officinale) on sperm dna fragmentation (sdf) in infertile men. materials and methods: this randomized double-blind, placebo-controlle...

conclusions in our study, no prominent effect was seen; therefore, in order to have a better perspective of crocin activity against cancerous cell lines, further studies are highly recommended. results the highest concentration of crocin significantly decreased ros production after 48 hours of treatment. however, crocin had no effect on the expression level of hsp (heat shock protein). addition...

prolonged local consumption of anethum graveolens leaves, as an antihyperlipimic and antihypercholesterolemic agent, has been associated in some patients with skin disorders such as darkening and pigmentation mainly in the exposed areas such as face and hands.anethum graveolens belongs to the umbelliferae family which is belived to be rich in photoactive furocoumarins. an oraganic extract of th...

background: the initial step in the diagnostic investigation of male infertility has been traditionally based on the conventional seminal profile. however, there are significant limitations regarding its ability to determine the underlying mechanisms that cause the disorder. sperm dna fragmentation has emerged as a potential causative factor of reproductive failure and its assessment has been s...

Background Sperm DNA fragmentation is known as an important cause of male infertility. The influence of sperm DNA damage on reproductive potential has been subject of many studies indicating various results and remaining the subject controversial. In this study, we investigated differences of the semen parameters and intracytoplasmic sperm injection (ICSI) outcome according to sperm DNA fragmen...

background: an effect of cryopreservation on human sperm is sublethal cryodamage, in which cell viability post-thaw is lost more rapidly at later times than in fresh cells. objective:  this study examined whether the addition of an antioxidant to cryopreservation medium could improve the post-thaw parameters and evaluation of sperm chromatin quality of cryopreserved human spermatozoa from men w...

Background: Techniques of sperm preparation require centrifugation to separate spermatozoa from the seminal plasma. The centrifugation can induce damage to the spermatozoa and increase reactive oxygen species(ROS) productionspecially in leukospermic speciemens that are associated with impaired function and fertilizing capacity. However in ICSI, fertilization can occure with damage DNA sperm but...

background: sperm dna fragmentation is known as an important cause of male infertility. the influence of sperm dna damage on reproductive potential has been subject of many studies indicating various results and remaining the subject controversial. in this study, we investigated differences of the semen parameters and intracytoplasmic sperm injection (icsi) outcome according to sperm dna fragme...